A specific clinical pattern Viktor Frankl identified — which he called "unemployment neurosis" — showed that depression tied to joblessness often stemmed less from material hardship itself than from unconsciously equating being unemployed with being useless, and equating uselessness with having a meaningless life. This distinction has a real, testable clinical implication: if the depression is actually about meaning rather than material circumstance, then restoring a sense of meaningful contribution should lift the depression even if the material hardship stays completely unchanged.
This doesn't argue that material circumstances don't matter — it argues that meaning and material comfort are separable variables, and that addressing the wrong one (trying to fix material hardship when the actual driver is a lost sense of contribution) can leave a real, solvable problem untouched.